MLchartDataset catalogue

Iodine I 131-labeled anti-CEA/anti-HSG bispecific monoclonal antibody TF2

Term · Oncology and biomedicine · MLC-T-ONC-014540

A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten radiolabeled with iodine I 131 (I131) with antigen-binding and radioisotopic activities. Iodine I 131-labeled anti-CEA/anti-HSG bispecific monoclonal antibody TF2 binds to the tumor-associated antigen (TAA) CEA on CEA-expressing tumor cells; these cells may then be radioimaged scintigraphically.

Table 1. Record
IdentifierMLC-T-ONC-014540
FieldOncology and biomedicine
Abbreviation131I-TF2
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014540",
  "term": "Iodine I 131-labeled anti-CEA/anti-HSG bispecific monoclonal antibody TF2",
  "field": "Oncology and biomedicine",
  "definition": "A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten radiolabeled with iodine I 131 (I131) with antigen-binding and radioisotopic activities. Iodine I 131-labeled anti-CEA/anti-HSG bispecific monoclonal antibody TF2 binds to the tumor-associated antigen (TAA) CEA on CEA-expressing tumor cells; these cells may then be radioimaged scintigraphically.",
  "abbreviation": "131I-TF2",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iodine-i-131-labeled-anti-cea-anti-hsg-bispecific-monoclonal-antibody-tf2/"
}

Record 9,521 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.