Iodine I 131-labeled anti-CEA/anti-HSG bispecific monoclonal antibody TF2
Term · Oncology and biomedicine · MLC-T-ONC-014540
A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten radiolabeled with iodine I 131 (I131) with antigen-binding and radioisotopic activities. Iodine I 131-labeled anti-CEA/anti-HSG bispecific monoclonal antibody TF2 binds to the tumor-associated antigen (TAA) CEA on CEA-expressing tumor cells; these cells may then be radioimaged scintigraphically.
| Identifier | MLC-T-ONC-014540 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | 131I-TF2 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-014540",
"term": "Iodine I 131-labeled anti-CEA/anti-HSG bispecific monoclonal antibody TF2",
"field": "Oncology and biomedicine",
"definition": "A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten radiolabeled with iodine I 131 (I131) with antigen-binding and radioisotopic activities. Iodine I 131-labeled anti-CEA/anti-HSG bispecific monoclonal antibody TF2 binds to the tumor-associated antigen (TAA) CEA on CEA-expressing tumor cells; these cells may then be radioimaged scintigraphically.",
"abbreviation": "131I-TF2",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/iodine-i-131-labeled-anti-cea-anti-hsg-bispecific-monoclonal-antibody-tf2/"
}
Record 9,521 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.