anti-CEA/anti-HSG bispecific monoclonal antibody TF2

{
  "id": "MLC-T-ONC-010468",
  "term": "anti-CEA/anti-HSG bispecific monoclonal antibody TF2",
  "field": "Oncology and biomedicine",
  "definition": "A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten. Anti-CEA/anti-HSG bispecific monoclonal antibody TF2 binds to the tumor associated antigen (TAA) CEA on CEA-expressing tumor cells. Subsequently, an HSG peptide-hapten carrying a radionuclide is administered, binding to the anti-HSG binding fragment on the BiMoAb. Depending on the characteristics of the radionuclide used, CEA-expressing tumor cells may then be radioimaged and/or treated radioimmunotherapeutically.",
  "synonyms": [
    "anti-CEA x anti-histamine-succinyl-glycine bispecific monoclonal antibody TF2"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-cea-anti-hsg-bispecific-monoclonal-antibody-tf2/"
}