lymphokine-activated killer cells

{
  "id": "MLC-T-ONC-014947",
  "term": "lymphokine-activated killer cells",
  "field": "Oncology and biomedicine",
  "definition": "Killer cell lymphocytes activated in the presence of interleukin-2 (IL-2). Lymphokine-activated killer cells (LAKs) are cytotoxic effector cells with an exceptionally wide target cell spectrum including normal and malignant cells of different origins. LAK cells exhibit a profound heterogeneity with regard to phenotype surface marker expression; it remains to be determined if they represent a unique cell lineage.",
  "abbreviation": "LAK",
  "synonyms": [
    "therapeutic lymphokine-activated killer cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/lymphokine-activated-killer-cells/"
}