monoclonal antibody Me1-14 F(ab')2

{
  "id": "MLC-T-ONC-015269",
  "term": "monoclonal antibody Me1-14 F(ab')2",
  "field": "Oncology and biomedicine",
  "definition": "The F(ab)2 fragment of Me1-14, a murine IgG2a monoclonal antibody directed against proteoglycan chondroitin sulfate-associated protein expressed by gliomas and melanomas. By binding to proteoglycan chondroitin sulfate-associated protein, monoclonal antibody Me1-14 F(ab')2 conjugated to a radioisotope may localize gliomas and melanomas when used as a tracer in radioimaging applications; in radioimmunotherapeutic applications, this agent conjugated to a radioisotope may be used to deliver targeted radiotoxicity to these tumors.",
  "abbreviation": "MOAB Me1-14 F(ab')2",
  "synonyms": [
    "Me1-14 F(ab')2"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/monoclonal-antibody-me1-14-f-ab-2/"
}