monoclonal antibody Mik-beta-1

{
  "id": "MLC-T-ONC-015270",
  "term": "monoclonal antibody Mik-beta-1",
  "field": "Oncology and biomedicine",
  "definition": "A murine monoclonal antibody directed against the beta subunit of the interleukin-2 receptor (IL-2R), expressed on resting T-lymphocytes, natural killer (NK) cells, and some leukemic cell types. Monoclonal antibody Mik-beta-1 prevents the binding of IL-2 to IL-2R beta, thereby inhibiting the IL-2-mediated proliferation and activation of T-cells.",
  "abbreviation": "MOAB Mik-beta-1",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/monoclonal-antibody-mik-beta-1/"
}