MUC1-targeted peptide GO-2-03-2C

{
  "id": "MLC-T-ONC-015333",
  "term": "MUC1-targeted peptide GO-2-03-2C",
  "field": "Oncology and biomedicine",
  "definition": "An optimized small peptide drug candidate targeting epithelial mucin (MUC1) with antineoplastic activity. MUC1-targeted peptide GO-203-2C interacts with oncoprotein MUC1 C-terminal subunit on the cell surface, thereby impeding cell-cell interactions, signaling, and metastasis. MUC1 antigen, a membrane bound glycoprotein expressed by most glandular and ductal epithelial cells, is over-expressed in many diverse human carcinomas including those of the breast, prostate, lung, colon, pancreas, and ovary, and has been associated with poor prognosis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/muc1-targeted-peptide-go-2-03-2c/"
}