Autologous MUC1-activated T cells

{
  "id": "MLC-T-ONC-011705",
  "term": "Autologous MUC1-activated T cells",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous T lymphocytes that have been activated against the tumor associated antigen (TAA) mucin-1 (MUC1), with potential immunomodulating and antineoplastic activities. Upon re-introduction into the patient, autologous MUC1-activated T cells specifically recognize and induce selective toxicity in MUC1-expressing tumor cells. MUC1, a glycoprotein overexpressed on the surface of a variety of cancer cells, plays a key role in tumor cell survival and proliferation.",
  "synonyms": [
    "autologous MUC1-activated T lymphocytes"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-muc1-activated-t-cells/"
}