sontuzumab

{
  "id": "MLC-T-ONC-016822",
  "term": "sontuzumab",
  "field": "Oncology and biomedicine",
  "definition": "A humanized monoclonal antibody directed against the tumor associated antigen (TAA) mucin-1 (MUC1), with potential antineoplastic activity. Upon administration, sontuzumab targets and binds to MUC1 expressed on the surface of tumor cells, which may activate the immune system to induce an antibody-dependent cellular cytotoxicity (ADCC) against MUC1-expressing tumor cells. MUC1, a glycoprotein overexpressed on the surface of a variety of cancer cells, plays a key role in tumor cell survival and proliferation.",
  "abbreviation": "HuHMFG1",
  "synonyms": [
    "epitumomab"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/sontuzumab/"
}