MUC1 peptide-poly-ICLC vaccine

{
  "id": "MLC-T-ONC-015329",
  "term": "MUC1 peptide-poly-ICLC vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A vaccine preparation containing mucus 1 (MUC1) peptide and the adjuvant poly-ICLC with potential immunostimulatory and antineoplastic activities. Upon administration, MUC1 peptide-poly-ICLC adjuvant vaccine may induce the host immune system to mount a cytotoxic T cell response against MUC1-expressing tumor cells. MUC1, a tumor associated antigen normally present on the lining of the human colon, may be overexpressed and/or mutated in a variety of cancer cell types. The adjuvant poly-ICLC, a ligand for toll-like receptor-3, induces the release of cytokines which may help boost the immune response against MUC1.",
  "synonyms": [
    "MUC1 peptide-poly-ICLC adjuvant vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/muc1-peptide-poly-iclc-vaccine/"
}