mycophenolic acid
Term · Oncology and biomedicine · MLC-T-ONC-015393
An antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate mofetil. Mycophenolic acid inhibits inosine monophosphate dehydrogenase (IMPDH), preventing the formation of guanosine monophosphate and synthesis of lymphocyte DNA that results in inhibition of lymphocyte proliferation, antibody production, cellular adhesion, and migration of T and B lymphocytes. Mycophenolic acid also has antibacterial, antifungal, and antiviral activities.
| Identifier | MLC-T-ONC-015393 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | MPA |
| Synonyms | acide mycophenolique; acido micofenolico; acidum mycophenolicum |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-015393",
"term": "mycophenolic acid",
"field": "Oncology and biomedicine",
"definition": "An antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate mofetil. Mycophenolic acid inhibits inosine monophosphate dehydrogenase (IMPDH), preventing the formation of guanosine monophosphate and synthesis of lymphocyte DNA that results in inhibition of lymphocyte proliferation, antibody production, cellular adhesion, and migration of T and B lymphocytes. Mycophenolic acid also has antibacterial, antifungal, and antiviral activities.",
"abbreviation": "MPA",
"synonyms": [
"acide mycophenolique",
"acido micofenolico",
"acidum mycophenolicum"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/mycophenolic-acid/"
}
Record 11,497 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.