related donor adenovirus-specific cytotoxic T cells

{
  "id": "MLC-T-ONC-016480",
  "term": "related donor adenovirus-specific cytotoxic T cells",
  "field": "Oncology and biomedicine",
  "definition": "A population of allogeneic related donor cytotoxic T lymphocytes (CTLs) specifically reactive to human adenovirus (Ad) with potential immunomodulating and anti-adenoviral activities. Upon infusion of related donor Ad-specific CTLs, these cells help reconstitute Ad-specific CTL responses in patients at risk of developing Ad infections after allogeneic stem cell transplant or in Ad-infected immunocompromised hosts. These related donor Ad-specific CTLs are manufactured with the CliniMACS Prodigy Cytokine Capture System which facilitates production of the Ad-specific CTLs.",
  "synonyms": [
    "related donor Ad-specific CTLs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/related-donor-adenovirus-specific-cytotoxic-t-cells/"
}