MLchartDataset catalogue

spiroplatin

Term · Oncology and biomedicine · MLC-T-ONC-016847

A synthetic derivative of cyclohexane sulfatoplatinum with antineoplastic properties. Spiroplatin induces DNA cross-links, thereby inhibiting DNA replication and RNA and protein synthesis. Similar to other platinum compounds, this agent has been shown to be mutagenic and carcinogenic.

Table 1. Record
IdentifierMLC-T-ONC-016847
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-016847",
  "term": "spiroplatin",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic derivative of cyclohexane sulfatoplatinum with antineoplastic properties. Spiroplatin induces DNA cross-links, thereby inhibiting DNA replication and RNA and protein synthesis. Similar to other platinum compounds, this agent has been shown to be mutagenic and carcinogenic.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/spiroplatin/"
}

Record 15,262 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.