TLR9 agonist SD-101

{
  "id": "MLC-T-ONC-017213",
  "term": "TLR9 agonist SD-101",
  "field": "Oncology and biomedicine",
  "definition": "A proprietary oligonucleotide with immunostimulatory activity. Immunostimulatory phosphorothiolate oligodeoxyribonucleotide SD-101 targets Toll-Like Receptor 9 (TLR9) found on a specialized subset of dendritic cells. The interaction of TLR9 with SD-101, in conjunction with an allergen or antigen, induces activation of memory T helper cells 1 (Th1) against a specific pathogen or allergen, thereby leading to long-lasting therapeutic effects. Furthermore, this agent does not cause a generalized activation of the immune system.",
  "abbreviation": "ISS-ODN SD-101",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/tlr9-agonist-sd-101/"
}