Phase I clinical studies

{
  "id": "MLC-T-CHM-008737",
  "term": "Phase I clinical studies",
  "field": "Chemistry",
  "definition": "The initial stage of human testing for a new drug, primarily focusing on safety, dosage range, and pharmacokinetics in a small group of healthy volunteers. These studies assess how the drug is absorbed, distributed, metabolized, and excreted by the body. They are not designed to evaluate the drug's efficacy for a specific condition.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "investigational new drug",
    "phase II clinical studies",
    "phase III clinical studies",
    "phase IV clinical studies"
  ],
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1746 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/phase-i-clinical-studies/"
}