Preformulation

{
  "id": "MLC-T-CHM-009382",
  "term": "Preformulation",
  "field": "Chemistry",
  "definition": "The stage of drug development where the physical and chemical properties of a new drug substance are characterized to provide a rational basis for formulation design. This involves studying solubility, stability, particle size, and polymorphism. The data gathered during preformulation guides the selection of excipients and the development of a stable and bioavailable dosage form.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "biopharmaceutics",
    "formulation",
    "pharmaceutics"
  ],
  "references": [
    "PAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 994 (https://doi.org/10.1351/PAC-REC-04-10-14)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/preformulation/"
}