Proof of concept

{
  "id": "MLC-T-CHM-013438",
  "term": "Proof of concept",
  "field": "Chemistry",
  "definition": "The demonstration that a particular idea, method, or product is feasible and has the potential to achieve its intended purpose. In medicinal chemistry, this involves showing that a therapeutic strategy or a drug candidate can elicit a desired biological effect in a relevant model system. This stage often precedes extensive development and clinical trials, providing preliminary evidence of efficacy.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "lead validation",
    "pivotal study"
  ],
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1748 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/proof-of-concept/"
}