anti-CD33 monoclonal antibody BI 836858

{
  "id": "MLC-T-ONC-010342",
  "term": "anti-CD33 monoclonal antibody BI 836858",
  "field": "Oncology and biomedicine",
  "definition": "An engineered, fully human, immunoglobulin (Ig) G1 anti-CD33 monoclonal antibody, with potential antineoplastic activity. Upon administration, anti-CD33 monoclonal antibody BI 836858 induces an antibody-dependent cellular cytotoxicity (ADCC) against CD33-expressing tumor cells, leading to cell death. CD33, a cell surface antigen expressed on normal non-pluripotent hematopoietic stem cells, is overexpressed on myeloid leukemia cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-cd33-monoclonal-antibody-bi-836858/"
}