Apamistamab

{
  "id": "MLC-T-ONC-011193",
  "term": "Apamistamab",
  "field": "Oncology and biomedicine",
  "definition": "A murine IgG1 anti-CD45 monoclonal antibody (MoAb) with immunotherapeutic activity. CD45 antigen, a receptor protein-tyrosine phosphatase essential for T cell development and lymphocyte activation, is expressed on virtually all leukocytes. Apamistamab has specificity for hematopoietic tissues and may be used in targeted immunotherapy.",
  "synonyms": [
    "anti-CD45 monoclonal antibody BC8",
    "monoclonal antibody BC8"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/apamistamab/"
}