indium In 111 anti-CD45 monoclonal antibody BC8

{
  "id": "MLC-T-ONC-014409",
  "term": "indium In 111 anti-CD45 monoclonal antibody BC8",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate containing the murine IgG1 anti-CD45 monoclonal antibody (MoAb) BC8 labeled with the gamma-emitting isotope indium 111 (In 111), with potential radioimaging application. Upon administration, indium In 111 anti-CD45 monoclonal antibody BC8 binds to CD45 antigen, a receptor protein tyrosine phosphatase expressed on the surface of most of the normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, radioactive In 111 allows for the detection of BC8 distribution and tumor localization using gamma scintigraphy.",
  "synonyms": [
    "In111 MOAB BC8",
    "indium In 111 MOAB BC8",
    "In 111 MOAB BC8",
    "In 111 monoclonal antibody BC8"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/indium-in-111-anti-cd45-monoclonal-antibody-bc8/"
}