autologous CAR-engineered regulatory T cells SBT777101

{
  "id": "MLC-T-ONC-011525",
  "term": "autologous CAR-engineered regulatory T cells SBT777101",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous T-regulatory cells (Tregs) that have been genetically modified to express a chimeric antigen receptor (CAR) targeting citrullinated proteins, with potential immunmodulating activity. Upon administration, the autologous CAR-engineered regulatory T cells SBT777101 target and bind to citrullinated proteins and may decrease inflammation and promote immunologic homeostasis. Citrullinated proteins are found in inflamed disease-associated tissues in many autoimmune and inflammatory diseases.",
  "synonyms": [
    "autologous CAR-engineered Treg cells SBT777101",
    "autologous CAR-Treg cells SBT777101",
    "autologous CAR-Tregs SBT-77-7101"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-car-engineered-regulatory-t-cells-sbt777101/"
}