Copper Cu 64 FAP-2286

{
  "id": "MLC-T-ONC-012743",
  "term": "Copper Cu 64 FAP-2286",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of FAP-2286, a fibroblast activation protein (FAP)-targeted peptide, labeled with the radioisotope copper Cu 64, with potential use as a tracer for FAP-expressing cells during positron emission tomography (PET). Upon administration of copper Cu 64 FAP-2286, the FAP-2286 moiety targets and binds to FAP-expressing cancer-associated fibroblasts (CAFs) and FAP-expressing tumor cells. Upon binding, FAP-expressing cells can be detected during PET imaging. FAP, a cell surface protein, is overexpressed on CAFs in the tumor microenvironment (TME) and certain tumor cells.",
  "synonyms": [
    "64Cu-FAP-2286",
    "copper-64 labeled FAP-2286"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/copper-cu-64-fap-2286/"
}