elacestrant hydrochloride

{
  "id": "MLC-T-ONC-013293",
  "term": "elacestrant hydrochloride",
  "field": "Oncology and biomedicine",
  "definition": "The hydrochloride salt form of elacestrant, an orally available, selective estrogen receptor degrader (SERD), with antineoplastic activity. Upon oral administration, elacestrant acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the proteosomal degradation of the receptor. This prevents ER-mediated signaling and inhibits proliferation of ER-expressing cancer cells.",
  "synonyms": [
    "RAD-1901 dihydrochloride",
    "RAD1901 dihydrochloride"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/elacestrant-hydrochloride/"
}