Fluorine F 18 NOS

{
  "id": "MLC-T-ONC-013689",
  "term": "Fluorine F 18 NOS",
  "field": "Oncology and biomedicine",
  "definition": "A radiotracer composed of an analog of the reversible nitric oxide synthase (NOS) inhibitor, 2-amino 4-methylpyridine, radiolabeled with fluorine F 18, with potential imaging activity upon positron emission tomography/computed tomography (PET/CT). Upon administration of fluorine F 18 NOS, the NOS moiety targets and binds to inducible NOS (iNOS). Upon PET/CT imaging, iNOS expression and thus the extent of inflammation can be assessed. iNOS expression is upregulated in a variety of inflammatory diseases and certain cancers and may invoke a chronic inflammatory state in tumor cells.",
  "synonyms": [
    "FNOS",
    "[18F]NOS",
    "18F NOS",
    "18F-NOS",
    "(18)F-NOS"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-nos/"
}