Arachnodactyly

{
  "id": "MLC-T-CHM-000759",
  "term": "Arachnodactyly",
  "field": "Chemistry",
  "definition": "A congenital physical condition characterized by abnormally long and slender fingers and toes, giving them a spider-like appearance. This trait is a classic feature of certain genetic disorders, most notably Marfan syndrome, which is a connective tissue disorder caused by mutations in the FBN1 gene. The Steinberg sign, where the thumb extends past the palm when the fist is clenched, is a clinical test for this condition.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 726 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/arachnodactyly/"
}