Attrition rate

Term · Chemistry · MLC-T-CHM-000939

The rate at which drug candidates are lost as they progress through the development stages on the way to the market. It is high: an often quoted estimate is that only one compound in ten thousand examined in early biological testing reaches the market. In clinical research the same word also names the dropout of participants from a study.

Table 1. Record
Identifier	MLC-T-CHM-000939
Field	Chemistry
Subject	Chemistry and Human Health
References	PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1728 (https://doi.org/10.1351/PAC-REC-12-11-23)

Record as JSON

{
  "id": "MLC-T-CHM-000939",
  "term": "Attrition rate",
  "field": "Chemistry",
  "definition": "The rate at which drug candidates are lost as they progress through the development stages on the way to the market. It is high: an often quoted estimate is that only one compound in ten thousand examined in early biological testing reaches the market. In clinical research the same word also names the dropout of participants from a study.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1728 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/attrition-rate/"
}

Record 1,011 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.