Disruption

{
  "id": "MLC-T-CHM-003318",
  "term": "Disruption",
  "field": "Chemistry",
  "definition": "A teratogenic effect involving the breakdown of a normally formed organ or tissue, leading to a structural anomaly. Unlike malformation, which arises from an intrinsically abnormal developmental process, disruption is caused by an extrinsic factor, such as a toxicant, infection, or vascular event, that interferes with development after it has begun. An example is an amputation of a fetal limb caused by an amniotic band.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 744 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/disruption/"
}