Drug-likeness

{
  "id": "MLC-T-CHM-003455",
  "term": "Drug-likeness",
  "field": "Chemistry",
  "definition": "A qualitative concept used in drug discovery to assess how closely a chemical compound resembles known oral drugs. This property is evaluated based on physicochemical parameters such as molecular weight, lipophilicity, hydrogen bond donors, and acceptors. Lipinski's Rule of Five provides a common set of guidelines for predicting oral drug-likeness.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 245 (https://doi.org/10.1515/pac-2012-1204)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/drug-likeness/"
}