Lipophilicity

{
  "id": "MLC-T-CHM-006665",
  "term": "Lipophilicity",
  "field": "Chemistry",
  "definition": "The physicochemical property of a molecule indicating its affinity for a lipophilic environment, such as a lipid membrane or a nonpolar solvent. It quantifies the tendency of a compound to partition into a lipid phase rather than an aqueous phase. This property is often expressed as a partition coefficient, such as log P for octanol-water partitioning.",
  "subject": "Physical and Biophysical Chemistry",
  "see_also": [
    "chromatography",
    "lipophilic",
    "moiety",
    "partition coefficient",
    "thin-layer chromatography"
  ],
  "references": [
    "PAC, 1972, 31, 577. 'Manual of Symbols and Terminology for Physicochemical Quantities and Units, Appendix II: Definitions, Terminology and Symbols in Colloid and Surface Chemistry' on page 607 (https://doi.org/10.1351/pac197231040577)",
    "PAC, 1994, 66, 1077. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)' on page 1123 (https://doi.org/10.1351/pac199466051077)",
    "PAC, 1997, 69, 1137. 'Glossary of terms used in computational drug design (IUPAC Recommendations 1997)' on page 1145 (https://doi.org/10.1351/pac199769051137)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/lipophilicity/"
}