MLchartDataset catalogue

Log P

Term · Chemistry · MLC-T-CHM-006749

The logarithm (base 10) of the partition coefficient, which is the ratio of the concentration of an un-ionized compound in an organic phase (typically n-octanol) to its concentration in an aqueous phase. It is a measure of a compound's lipophilicity or hydrophobicity. Log P values are widely used in medicinal chemistry to predict drug absorption, distribution, metabolism, and excretion.

Table 1. Record
IdentifierMLC-T-CHM-006749
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 249 (https://doi.org/10.1515/pac-2012-1204)
Record as JSON
{
  "id": "MLC-T-CHM-006749",
  "term": "Log P",
  "field": "Chemistry",
  "definition": "The logarithm (base 10) of the partition coefficient, which is the ratio of the concentration of an un-ionized compound in an organic phase (typically n-octanol) to its concentration in an aqueous phase. It is a measure of a compound's lipophilicity or hydrophobicity. Log P values are widely used in medicinal chemistry to predict drug absorption, distribution, metabolism, and excretion.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 249 (https://doi.org/10.1515/pac-2012-1204)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/log-p/"
}

Record 7,148 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.