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CLOGP values

Term · Chemistry · MLC-T-CHM-002125

Numerical estimations of the octanol-water partition coefficient, derived through computational methods. These values quantify the lipophilicity of a chemical compound, indicating its preference for a lipid (octanol) phase over an aqueous (water) phase. CLOGP values are widely employed in drug design and toxicology to predict how a substance will behave in biological systems.

Table 1. Record
IdentifierMLC-T-CHM-002125
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 1997, 69, 1137. 'Glossary of terms used in computational drug design (IUPAC Recommendations 1997)' on page 1140 (https://doi.org/10.1351/pac199769051137)
See alsoPartition; Quantitative structure-activity relationship
Record as JSON
{
  "id": "MLC-T-CHM-002125",
  "term": "CLOGP values",
  "field": "Chemistry",
  "definition": "Numerical estimations of the octanol-water partition coefficient, derived through computational methods. These values quantify the lipophilicity of a chemical compound, indicating its preference for a lipid (octanol) phase over an aqueous (water) phase. CLOGP values are widely employed in drug design and toxicology to predict how a substance will behave in biological systems.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "partition",
    "quantitative structure-activity relationship"
  ],
  "references": [
    "PAC, 1997, 69, 1137. 'Glossary of terms used in computational drug design (IUPAC Recommendations 1997)' on page 1140 (https://doi.org/10.1351/pac199769051137)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/clogp-values/"
}

Record 2,274 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.