Clog P
Term · Chemistry · MLC-T-CHM-002124
A calculated logarithm of the octanol-water partition coefficient, representing the lipophilicity of a chemical compound. It quantifies the distribution of a substance between an octanol phase and an aqueous phase, serving as an indicator of its membrane permeability and bioavailability. This value is frequently used in drug design to predict absorption and distribution.
| Identifier | MLC-T-CHM-002124 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 243 (https://doi.org/10.1515/pac-2012-1204) |
Record as JSON
{
"id": "MLC-T-CHM-002124",
"term": "Clog P",
"field": "Chemistry",
"definition": "A calculated logarithm of the octanol-water partition coefficient, representing the lipophilicity of a chemical compound. It quantifies the distribution of a substance between an octanol phase and an aqueous phase, serving as an indicator of its membrane permeability and bioavailability. This value is frequently used in drug design to predict absorption and distribution.",
"subject": "Chemistry and Human Health",
"references": [
"PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 243 (https://doi.org/10.1515/pac-2012-1204)"
],
"url": "https://mlchart.com/terminology/chemistry/clog-p/"
}
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