Octanol-water partition ratio
Term · Chemistry · MLC-T-CHM-008191
The ratio of the concentration of a chemical in n-octanol to its concentration in water at equilibrium and a specified temperature. This ratio, often expressed as log P, is a measure of a compound's lipophilicity or hydrophobicity. It is widely used in pharmacology and environmental science to predict a substance's distribution in biological systems or the environment.
| Identifier | MLC-T-CHM-008191 |
|---|---|
| Field | Chemistry |
| Subject | Organic and Biomolecular Chemistry |
| Synonyms | partition ratio; water/octanol partition coefficient |
| References | PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 474 (https://doi.org/10.1515/pac-2018-1010) |
Record as JSON
{
"id": "MLC-T-CHM-008191",
"term": "Octanol-water partition ratio",
"field": "Chemistry",
"definition": "The ratio of the concentration of a chemical in n-octanol to its concentration in water at equilibrium and a specified temperature. This ratio, often expressed as log P, is a measure of a compound's lipophilicity or hydrophobicity. It is widely used in pharmacology and environmental science to predict a substance's distribution in biological systems or the environment.",
"synonyms": [
"partition ratio",
"water/octanol partition coefficient"
],
"subject": "Organic and Biomolecular Chemistry",
"references": [
"PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 474 (https://doi.org/10.1515/pac-2018-1010)"
],
"url": "https://mlchart.com/terminology/chemistry/octanol-water-partition-ratio/"
}
Record 8,706 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.