Hansch-Fujita π-constant

{
  "id": "MLC-T-CHM-005093",
  "term": "Hansch-Fujita π-constant",
  "field": "Chemistry",
  "definition": "A substituent constant that quantifies the lipophilicity or hydrophobicity of a chemical group relative to hydrogen. It is derived from the partition coefficient (log P) of a substituted compound compared to its unsubstituted parent compound. A positive π-constant indicates increased lipophilicity, while a negative value indicates increased hydrophilicity.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "log P"
  ],
  "references": [
    "PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 247 (https://doi.org/10.1515/pac-2012-1204)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/hansch-fujita-p-constant/"
}