Phenotypic screening

{
  "id": "MLC-T-CHM-008760",
  "term": "Phenotypic screening",
  "field": "Chemistry",
  "definition": "A drug discovery approach where compounds are tested for their ability to induce a desired change in cell or organism phenotype, without necessarily knowing the specific molecular target. This method contrasts with target-based screening, which focuses on specific protein interactions. It has led to the discovery of many first-in-class drugs.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "small inhibitory double-stranded RNA"
  ],
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1747 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/phenotypic-screening/"
}