Off-target effect

{
  "id": "MLC-T-CHM-008203",
  "term": "Off-target effect",
  "field": "Chemistry",
  "definition": "An unintended biological activity of a drug or chemical compound on a molecule other than its primary, intended target. This can lead to undesirable side effects or toxicity in a biological system. Such effects are often identified during drug discovery and development through broad screening assays.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1744 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/off-target-effect/"
}