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Privileged structure

Term · Chemistry · MLC-T-CHM-009481

A molecular scaffold or core structure that is capable of binding to multiple biological targets with high affinity. These structures often serve as starting points for the design of new drugs due to their inherent versatility and favorable pharmacological properties. Examples include benzodiazepines and dihydropyridines, which are found in many therapeutic agents.

Table 1. Record
IdentifierMLC-T-CHM-009481
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1748 (https://doi.org/10.1351/PAC-REC-12-11-23)
See alsoScaffold
Record as JSON
{
  "id": "MLC-T-CHM-009481",
  "term": "Privileged structure",
  "field": "Chemistry",
  "definition": "A molecular scaffold or core structure that is capable of binding to multiple biological targets with high affinity. These structures often serve as starting points for the design of new drugs due to their inherent versatility and favorable pharmacological properties. Examples include benzodiazepines and dihydropyridines, which are found in many therapeutic agents.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "scaffold"
  ],
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1748 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/privileged-structure/"
}

Record 10,067 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.