Selectivity assay

{
  "id": "MLC-T-CHM-010687",
  "term": "Selectivity assay",
  "field": "Chemistry",
  "definition": "A biochemical or cellular assay designed to evaluate the ability of a compound to preferentially interact with a specific target, such as an enzyme or receptor, over other related targets. This type of assay quantifies the compound's binding affinity or inhibitory potency across a panel of targets. High selectivity is generally desired for therapeutic agents to minimize off-target effects and toxicity.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "counter-screen"
  ],
  "references": [
    "PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1154 (https://doi.org/10.1351/PAC-REC-09-05-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/selectivity-assay/"
}