Homogeneous binding assay
Term · Chemistry · MLC-T-CHM-005361
A type of biochemical assay that measures the interaction between two or more molecules in a single solution without requiring physical separation of bound from unbound components. The signal, often fluorescence-based, changes upon binding, allowing direct quantification of the interaction. This method is frequently employed in drug discovery for screening ligand-receptor interactions.
| Identifier | MLC-T-CHM-005361 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1143 (https://doi.org/10.1351/PAC-REC-09-05-03) |
| See also | Fluorescence polarisation assay |
Record as JSON
{
"id": "MLC-T-CHM-005361",
"term": "Homogeneous binding assay",
"field": "Chemistry",
"definition": "A type of biochemical assay that measures the interaction between two or more molecules in a single solution without requiring physical separation of bound from unbound components. The signal, often fluorescence-based, changes upon binding, allowing direct quantification of the interaction. This method is frequently employed in drug discovery for screening ligand-receptor interactions.",
"subject": "Chemistry and Human Health",
"see_also": [
"fluorescence polarisation assay"
],
"references": [
"PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1143 (https://doi.org/10.1351/PAC-REC-09-05-03)"
],
"url": "https://mlchart.com/terminology/chemistry/homogeneous-binding-assay/"
}
Record 5,681 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.