Surface plasmon resonance assay

Term · Chemistry · MLC-T-CHM-011658

An optical technique used to detect and quantify molecular interactions in real time without the need for labels. It measures changes in refractive index at a metal-dielectric interface caused by binding events on a sensor surface. This method is widely applied in drug discovery for determining binding kinetics and affinity constants.

Table 1. Record
Identifier	MLC-T-CHM-011658
Field	Chemistry
Subject	Chemistry and Human Health
Synonyms	SPR Assay
References	PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1155 (https://doi.org/10.1351/PAC-REC-09-05-03)

Record as JSON

{
  "id": "MLC-T-CHM-011658",
  "term": "Surface plasmon resonance assay",
  "field": "Chemistry",
  "definition": "An optical technique used to detect and quantify molecular interactions in real time without the need for labels. It measures changes in refractive index at a metal-dielectric interface caused by binding events on a sensor surface. This method is widely applied in drug discovery for determining binding kinetics and affinity constants.",
  "synonyms": [
    "SPR Assay"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1155 (https://doi.org/10.1351/PAC-REC-09-05-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/surface-plasmon-resonance-assay/"
}

Record 12,424 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.