anti-PSCA monoclonal antibody AGS-1C4D4

{
  "id": "MLC-T-ONC-011047",
  "term": "anti-PSCA monoclonal antibody AGS-1C4D4",
  "field": "Oncology and biomedicine",
  "definition": "An IgG1k fully human monoclonal antibody directed against the human prostate stem cell antigen (PSCA) with potential antineoplastic activity. Anti-PSCA fully human monoclonal antibody MK4721 selectively targets and binds to PSCA, triggering complement-dependent cell lysis and antibody-dependent cell-mediated cytotoxicity in tumor cells expressing PSCA. PSCA is a glycosyl-phosphatidylinositol (GPI)-linked cell surface antigen found in cancers of the bladder, pancreas, and prostate.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-psca-monoclonal-antibody-ags-1c4d4/"
}