biropepimut-S

{
  "id": "MLC-T-ONC-012024",
  "term": "biropepimut-S",
  "field": "Oncology and biomedicine",
  "definition": "A proprietary, peptide cancer vaccine comprised of multiple peptides derived from human melanoma antigen A3 (MAGE-A3; MAGEA3), with potential immunostimulating and antineoplastic activities. Upon administration, biropepimut-S may stimulate the immune system to mount specific responses from B-cells, and CD4-positive and CD8-positive cells against tumor cells expressing MAGE-A3, resulting in tumor cell lysis. MAGE-A3, a tumor-associated antigen (TAA), is overexpressed by a variety of cancer cell types.",
  "synonyms": [
    "GL-0817 Vaccine",
    "MAGE-A3 peptide vaccine GL-0817",
    "MAGE-A3 multipeptide vaccine GL-0817"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/biropepimut-s/"
}