Beta-sheet breaker

{
  "id": "MLC-T-CHM-001205",
  "term": "Beta-sheet breaker",
  "field": "Chemistry",
  "definition": "A molecule designed to disrupt the formation or stability of beta-sheet structures in proteins. These agents typically interfere with the hydrogen bonding or steric interactions that stabilize the beta-sheet conformation. Such molecules are investigated for their potential to inhibit protein aggregation in neurodegenerative diseases like Alzheimer's.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "beta-sheet"
  ],
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1728 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/beta-sheet-breaker/"
}