Amyloid

{
  "id": "MLC-T-CHM-000529",
  "term": "Amyloid",
  "field": "Chemistry",
  "definition": "An insoluble fibrous protein aggregate that can accumulate abnormally in tissues and organs, a condition known as amyloidosis. These proteins misfold into a characteristic cross-beta sheet conformation, making them resistant to normal cellular clearance mechanisms. The presence of amyloid deposits is a pathological hallmark of several neurodegenerative conditions, including Alzheimer's disease, where the primary component is amyloid-beta peptide.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1122 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/amyloid/"
}