Inclusion body

{
  "id": "MLC-T-CHM-005760",
  "term": "Inclusion body",
  "field": "Chemistry",
  "definition": "An abnormal, insoluble aggregate of protein or viral particles that forms within the nucleus or cytoplasm of a cell. These structures result from the misfolding and accumulation of specific proteins, a process associated with several neurodegenerative diseases, including Alzheimer's and Parkinson's disease. Inclusion bodies are identified through microscopy after specific staining, appearing as distinct, dense masses within the affected cells.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Alzheimer disease",
    "misfolded protein",
    "neurodegenerative disease",
    "β-amyloid"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 875 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/inclusion-body/"
}