Protein folding

{
  "id": "MLC-T-CHM-013445",
  "term": "Protein folding",
  "field": "Chemistry",
  "definition": "The physical process by which a polypeptide chain acquires its native, three-dimensional structure, a conformation that is biologically functional. This complex process involves the polypeptide chain folding into a specific, stable arrangement driven by hydrophobic interactions, hydrogen bonds, and other forces. Misfolding of proteins is associated with a number of diseases, including Alzheimer's disease and cystic fibrosis.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1160 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/protein-folding/"
}