Protein-protein interaction

{
  "id": "MLC-T-CHM-009591",
  "term": "Protein-protein interaction",
  "field": "Chemistry",
  "definition": "The specific physical contact between two or more protein molecules, driven by electrostatic forces, hydrogen bonds, and hydrophobic effects. These associations can be stable, forming permanent multi-protein complexes, or transient, mediating steps in signaling pathways and metabolic processes. Analytical methods like the yeast two-hybrid system and affinity purification coupled with mass spectrometry are used for their detection and characterization.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1185 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/protein-protein-interaction/"
}