G protein-coupled receptor

{
  "id": "MLC-T-CHM-004737",
  "term": "G protein-coupled receptor",
  "field": "Chemistry",
  "definition": "A large family of transmembrane proteins that convert extracellular stimuli into intracellular signals through interaction with G proteins. Upon binding an external ligand, such as a hormone or neurotransmitter, the receptor undergoes a conformational change that activates a G protein on the cell's interior. These receptors possess a characteristic structure of seven alpha-helical segments that span the cell membrane.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 871 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/g-protein-coupled-receptor/"
}