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Metabotropic receptor

Term · Chemistry · MLC-T-CHM-007248

A type of membrane receptor that acts through a secondary messenger when a ligand binds to it. Unlike ionotropic receptors, it does not form an ion channel pore but instead initiates a cascade of intracellular signals. A common mechanism involves the activation of a G protein, which then modulates the activity of other proteins, such as enzymes or ion channels, leading to a slower but more prolonged cellular response.

Table 1. Record
IdentifierMLC-T-CHM-007248
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1741 (https://doi.org/10.1351/PAC-REC-12-11-23)
See alsoG protein; Ionotropic receptor
Record as JSON
{
  "id": "MLC-T-CHM-007248",
  "term": "Metabotropic receptor",
  "field": "Chemistry",
  "definition": "A type of membrane receptor that acts through a secondary messenger when a ligand binds to it. Unlike ionotropic receptors, it does not form an ion channel pore but instead initiates a cascade of intracellular signals. A common mechanism involves the activation of a G protein, which then modulates the activity of other proteins, such as enzymes or ion channels, leading to a slower but more prolonged cellular response.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "G protein",
    "ionotropic receptor"
  ],
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1741 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/metabotropic-receptor/"
}

Record 7,680 of 13,678 in Chemistry terminology (MLC-0109). Request the full dataset.