Chromosome deletion

{
  "id": "MLC-T-CHM-002056",
  "term": "Chromosome deletion",
  "field": "Chemistry",
  "definition": "A chromosomal abnormality in which a chromosome, or part of one, is lost. Terminal deletions remove the end of a chromosome arm and interstitial deletions remove a segment from within an arm. Clinical effects depend on the size of the lost region and the genes it carries, as in cri-du-chat syndrome, which results from loss of part of the short arm of chromosome 5.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 736 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/chromosome-deletion/"
}