Cumulative effect

{
  "id": "MLC-T-CHM-002775",
  "term": "Cumulative effect",
  "field": "Chemistry",
  "definition": "The total change that builds up across successive exposures to a chemical or to radiation, each one adding to the response already produced by earlier ones. One route is accumulation of the agent in the body because intake outpaces elimination. Another is irreversible damage that adds up from dose to dose even though the agent is cleared completely between them.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1200 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/cumulative-effect/"
}